{"id":7149,"date":"2023-01-11T11:52:18","date_gmt":"2023-01-11T10:52:18","guid":{"rendered":"https:\/\/bio-pat.org\/?p=7149"},"modified":"2023-01-11T12:03:31","modified_gmt":"2023-01-11T11:03:31","slug":"fyonibio-signed-service-agreement-with-adivo-gmbh","status":"publish","type":"post","link":"https:\/\/bio-pat.org\/en\/fyonibio-signed-service-agreement-with-adivo-gmbh","title":{"rendered":"FyoniBio signed Service Agreement with Adivo GmbH"},"content":{"rendered":"<p><span class=\"break-words\"><span dir=\"ltr\"><a href=\"http:\/\/www.fyonibio.com\" data-attribute-index=\"0\" data-entity-hovercard-id=\"urn:li:fs_miniCompany:72432432\" data-entity-type=\"MINI_COMPANY\">FyoniBio GmbH<\/a>, member of the<a href=\"https:\/\/bio-pat.org\/www.bio-pat.org\" target=\"_blank\" rel=\"noopener noreferrer\"> Bio-PAT network<\/a>, signed a Service Agreement with adivo.It covers<\/span><\/span> the generation of a production cell line for their canine therapeutic mAb candidate.<\/p>\n<p class=\"has-text-align-left\">For the project, FyoniBio will use its versatile CHOnamite\u00ae cell line development platform, that integrates a high-performance Transposase technology and comprises various host<br \/>\ncell lines to select the most suitable cell line to produce adivo\u2019s canine mAb format at the highest quality and yield.<\/p>\n<p>&nbsp;<\/p>\n<p><strong>Press release<\/strong><\/p>\n<p><strong><span id=\"page3R_mcid27\" class=\"markedContent\"><span dir=\"ltr\" role=\"presentation\">Berlin, Germany and<\/span> <span dir=\"ltr\" role=\"presentation\">Munich<\/span><span dir=\"ltr\" role=\"presentation\">,<\/span> <span dir=\"ltr\" role=\"presentation\">Germany<\/span><span dir=\"ltr\" role=\"presentation\">,<\/span> <span dir=\"ltr\" role=\"presentation\">January<\/span> <span dir=\"ltr\" role=\"presentation\">1<\/span><span dir=\"ltr\" role=\"presentation\">0,<\/span> <span dir=\"ltr\" role=\"presentation\">202<\/span><span dir=\"ltr\" role=\"presentation\">3<\/span><\/span><\/strong><\/p>\n<p><span id=\"page3R_mcid28\" class=\"markedContent\"><span dir=\"ltr\" role=\"presentation\">FyoniBio<\/span><span dir=\"ltr\" role=\"presentation\">, a CDO expert specialized in tailored cell line development and adivo a leader in<\/span> <span dir=\"ltr\" role=\"presentation\">discovering species<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">specific therapeutic antibodies for pets are pleased to announce the<\/span> <span dir=\"ltr\" role=\"presentation\">signing of a cell line development agreement. adivo is transitioning its most advanc<\/span><span dir=\"ltr\" role=\"presentation\">ed<\/span> <span dir=\"ltr\" role=\"presentation\">proprietary therapeutic<\/span> <span dir=\"ltr\" role=\"presentation\">canine mAb<\/span> <span dir=\"ltr\" role=\"presentation\">candidate, which has been granted the limited<\/span> <span dir=\"ltr\" role=\"presentation\">market authorization status by the European Medicines Agency (EMA) into first<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">in<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">animal<\/span> <span dir=\"ltr\" role=\"presentation\">studies.<\/span><\/span><\/p>\n<p><span id=\"page3R_mcid29\" class=\"markedContent\"><span dir=\"ltr\" role=\"presentation\">For the project, FyoniBio will use its versatile CHOnamite<\/span><span dir=\"ltr\" role=\"presentation\">\u00ae<\/span> <span dir=\"ltr\" role=\"presentation\">cell line devel<\/span><span dir=\"ltr\" role=\"presentation\">opment platform<\/span><span dir=\"ltr\" role=\"presentation\">,<\/span> <span dir=\"ltr\" role=\"presentation\">that integrates a high<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">performance Transposase technology and<\/span> <span dir=\"ltr\" role=\"presentation\">compri<\/span><span dir=\"ltr\" role=\"presentation\">ses<\/span> <span dir=\"ltr\" role=\"presentation\">various host<\/span> <span dir=\"ltr\" role=\"presentation\">cell lines to select the most suitable cell line<\/span> <span dir=\"ltr\" role=\"presentation\">to produce<\/span> <span dir=\"ltr\" role=\"presentation\">a<\/span><span dir=\"ltr\" role=\"presentation\">divo<\/span><span dir=\"ltr\" role=\"presentation\">&#8216;s<\/span> <span dir=\"ltr\" role=\"presentation\">canine<\/span> <span dir=\"ltr\" role=\"presentation\">mAb format<\/span> <span dir=\"ltr\" role=\"presentation\">at<\/span> <span dir=\"ltr\" role=\"presentation\">the <\/span><span dir=\"ltr\" role=\"presentation\">highest<\/span> <span dir=\"ltr\" role=\"presentation\">quality and yield.<\/span><\/span><\/p>\n<p><span id=\"page3R_mcid30\" class=\"markedContent\"><span dir=\"ltr\" role=\"presentation\">&#8220;<\/span><span dir=\"ltr\" role=\"presentation\">We are delighted with this very collaborative project partnership with<\/span> <span dir=\"ltr\" role=\"presentation\">a<\/span><span dir=\"ltr\" role=\"presentation\">divo, which<\/span> <span dir=\"ltr\" role=\"presentation\">demonstrates an excellent fit between the project teams on both sides and that ou <\/span><span dir=\"ltr\" role=\"presentation\">CHOnamite<\/span><span dir=\"ltr\" role=\"presentation\">\u00ae<\/span> <span dir=\"ltr\" role=\"presentation\">platform is ideally suited to generate highly productive cell lines for canine<\/span> <span dir=\"ltr\" role=\"presentation\">antibodies as well<\/span><span dir=\"ltr\" role=\"presentation\">,<\/span><span dir=\"ltr\" role=\"presentation\">\u201d<\/span> <span dir=\"ltr\" role=\"presentation\">outlined Dr. Lars St<\/span><span dir=\"ltr\" role=\"presentation\">\u00f6<\/span><span dir=\"ltr\" role=\"presentation\">ckl, Managing Director at FyoniBio.<\/span><\/span><span id=\"page3R_mcid31\" class=\"markedContent\"><\/span><\/p>\n<p><span id=\"page26R_mcid0\" class=\"markedContent\"><span dir=\"ltr\" role=\"presentation\">\u201c<\/span><span dir=\"ltr\" role=\"presentation\">We are excited to work with FyoniBio, whom we have chosen for their extensive <\/span><span dir=\"ltr\" role=\"presentation\">experience in biopharma development and their ability to provide tailor<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">made services for<\/span> <span dir=\"ltr\" role=\"presentation\">companie<\/span><span dir=\"ltr\" role=\"presentation\">s of various sizes and at different development stages<\/span><span dir=\"ltr\" role=\"presentation\">.<\/span> <span dir=\"ltr\" role=\"presentation\">Advancing a product<\/span> <span dir=\"ltr\" role=\"presentation\">candidate from lab<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">scale manufacturing to providing trial<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">grade material is a pressure<\/span> <span dir=\"ltr\" role=\"presentation\">test for any therapeutic project and a significant value inflection point,<\/span><span dir=\"ltr\" role=\"presentation\">\u201c<\/span> <span dir=\"ltr\" role=\"presentation\">commented Dr.<\/span> <span dir=\"ltr\" role=\"presentation\">Phi<\/span><span dir=\"ltr\" role=\"presentation\">lipp Baer, Chief Scientific Officer of adivo.<\/span><\/span><span id=\"page26R_mcid1\" class=\"markedContent\"> <\/span><\/p>\n<p>&nbsp;<\/p>\n<p><strong><span id=\"page26R_mcid1\" class=\"markedContent\"><span dir=\"ltr\" role=\"presentation\">FyoniBio Facts<\/span><\/span><\/strong><\/p>\n<p><span id=\"page26R_mcid2\" class=\"markedContent\"><\/span><span id=\"page26R_mcid2\" class=\"markedContent\"><span dir=\"ltr\" role=\"presentation\">FyoniBio<\/span><span dir=\"ltr\" role=\"presentation\">\u2019<\/span><span dir=\"ltr\" role=\"presentation\">s<\/span> <span dir=\"ltr\" role=\"presentation\">ISO<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">9001 certified service portfolio covers the development chain from cell line <\/span><span dir=\"ltr\" role=\"presentation\">development, process development and in<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">depth analytical characterization, including <\/span><span dir=\"ltr\" role=\"presentation\">bioassays and clinical sample monitoring under GCLP. FyoniBio<\/span><span dir=\"ltr\" role=\"presentation\">\u2019<\/span><span dir=\"ltr\" role=\"presentation\">s expertise builds on the<\/span> <span dir=\"ltr\" role=\"presentation\">l<\/span><span dir=\"ltr\" role=\"presentation\">ong<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">standing experience of our scientists who have developed various cell lines and<\/span> <span dir=\"ltr\" role=\"presentation\">processes<\/span> <span dir=\"ltr\" role=\"presentation\">which<\/span> <span dir=\"ltr\" role=\"presentation\">entered late<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">stage clinical trials. Our customized approaches enable<\/span> <span dir=\"ltr\" role=\"presentation\">rapid, high<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">titer cell line development in various mammalian host cell lines specialize<\/span><span dir=\"ltr\" role=\"presentation\">d<\/span> <span dir=\"ltr\" role=\"presentation\">in<\/span> <span dir=\"ltr\" role=\"presentation\">meeting individual product requirements. Besides our CHOnamite<\/span><span dir=\"ltr\" role=\"presentation\">\u00ae<\/span> <span dir=\"ltr\" role=\"presentation\">platform, we provide<\/span> <span dir=\"ltr\" role=\"presentation\">the human GEX<\/span><span dir=\"ltr\" role=\"presentation\">\u00ae<\/span> <span dir=\"ltr\" role=\"presentation\">platform, which is particularly suited for recombinant proteins with<\/span> <span dir=\"ltr\" role=\"presentation\">complex glycan structures. Further<\/span><span dir=\"ltr\" role=\"presentation\">more<\/span> <span dir=\"ltr\" role=\"presentation\">FyoniBio is highly skilled<\/span> <span dir=\"ltr\" role=\"presentation\">in<\/span> <span dir=\"ltr\" role=\"presentation\">mass spectrom<\/span><span dir=\"ltr\" role=\"presentation\">etry<\/span> <span dir=\"ltr\" role=\"presentation\">based in<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">depth analytical characterization of biopharmaceutical<\/span><span dir=\"ltr\" role=\"presentation\">s<\/span> <span dir=\"ltr\" role=\"presentation\">and offers the whole<\/span> <span dir=\"ltr\" role=\"presentation\">package of clinical sample analysis from assay establishment, validation and measurement<\/span> <span dir=\"ltr\" role=\"presentation\">of clinical samples under GCLP.<\/span><\/span><\/p>\n<p><span id=\"page26R_mcid3\" class=\"markedContent\"><\/span><span id=\"page26R_mcid3\" class=\"markedContent\"><span dir=\"ltr\" role=\"presentation\">All services are established according<\/span> <span dir=\"ltr\" role=\"presentation\">to<\/span> <span dir=\"ltr\" role=\"presentation\">o<\/span><span dir=\"ltr\" role=\"presentation\">ur internal quality management system to <\/span><span dir=\"ltr\" role=\"presentation\">assure compliance with international ISO standard and meeting international GMP<\/span> <span dir=\"ltr\" role=\"presentation\">standards.<\/span><\/span><span id=\"page26R_mcid4\" class=\"markedContent\"><\/span><span id=\"page26R_mcid5\" class=\"markedContent\"><br role=\"presentation\" \/><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><span id=\"page26R_mcid5\" class=\"markedContent\"><strong><span dir=\"ltr\" role=\"presentation\">a<\/span><span dir=\"ltr\" role=\"presentation\">divo<\/span> <span dir=\"ltr\" role=\"presentation\">Facts<\/span><\/strong><\/span><\/p>\n<p><span id=\"page26R_mcid6\" class=\"markedContent\"><span dir=\"ltr\" role=\"presentation\">a<\/span><span dir=\"ltr\" role=\"presentation\">divo<\/span> <span dir=\"ltr\" role=\"presentation\">is forging a new era for companion animal health. Our proprietary phage display<\/span> <span dir=\"ltr\" role=\"presentation\">antibody<\/span> <span dir=\"ltr\" role=\"presentation\">libraries deliver species<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">specific drugs for a growing market need. We apply our<\/span> <span dir=\"ltr\" role=\"presentation\">extensive drug discovery and protein engineering know<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">how to address cancer, chronic<\/span> <span dir=\"ltr\" role=\"presentation\">inflammatory diseases and other serious conditions in pets. Together with our partners,<\/span> <span dir=\"ltr\" role=\"presentation\">we<\/span> <span dir=\"ltr\" role=\"presentation\">create the best possible therapeutics for our beloved furry friends. For further <\/span><span dir=\"ltr\" role=\"presentation\">information, please visit:<\/span><\/span><span id=\"page26R_mcid7\" class=\"markedContent\"> <span dir=\"ltr\" role=\"presentation\"><a href=\"http:\/\/www.adivo.vet\">www.adivo.vet<\/a>\/.<\/span><\/span><span id=\"page26R_mcid8\" class=\"markedContent\"><\/span><span id=\"page26R_mcid9\" class=\"markedContent\"><\/span><\/p>\n<div class=\"page\" role=\"region\" data-page-number=\"3\" aria-label=\"Seite 3\" data-loaded=\"true\">\n<div class=\"canvasWrapper\"><\/div>\n<\/div>\n<p><span id=\"page36R_mcid0\" class=\"markedContent\"><span dir=\"ltr\" role=\"presentation\"><span style=\"text-decoration: underline;\">FyoniBio Contact<\/span>:<\/span><\/span><span id=\"page36R_mcid1\" class=\"markedContent\"><br role=\"presentation\" \/><span dir=\"ltr\" role=\"presentation\">Dr. Ulrike Scheffler; Senior<\/span> <span dir=\"ltr\" role=\"presentation\">Director Business Development<\/span><br role=\"presentation\" \/><span dir=\"ltr\" role=\"presentation\">E<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">mail:<\/span><\/span><a href=\"mailto:contact@fyonibio.com\"><span id=\"page36R_mcid2\" class=\"markedContent\"> <span dir=\"ltr\" role=\"presentation\">contact@fyonibio.com<\/span><\/span><\/a><span id=\"page36R_mcid3\" class=\"markedContent\"><br role=\"presentation\" \/><span dir=\"ltr\" aria-owns=\"pdfjs_internal_id_39R\">Phone: +49 (0) 17619489825<\/span><\/span><span id=\"page36R_mcid4\" class=\"markedContent\"><br role=\"presentation\" \/><a href=\"http:\/\/www.fyonibio.com\"><span dir=\"ltr\" role=\"presentation\">www.fyonibio.com<\/span><\/a><\/span><span id=\"page36R_mcid5\" class=\"markedContent\"><\/span><span id=\"page36R_mcid6\" class=\"markedContent\"><\/span><span id=\"page36R_mcid7\" class=\"markedContent\"><br role=\"presentation\" \/><span style=\"text-decoration: underline;\"><span dir=\"ltr\" role=\"presentation\">a<\/span><span dir=\"ltr\" role=\"presentation\">divo<\/span> <span dir=\"ltr\" role=\"presentation\">Contact:<\/span><\/span><\/span><span id=\"page36R_mcid8\" class=\"markedContent\"><br role=\"presentation\" \/><span dir=\"ltr\" role=\"presentation\">Dr. Kathrin Ladetzki<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">Baehs<\/span><span dir=\"ltr\" role=\"presentation\">, CEO<\/span><\/span><span id=\"page36R_mcid9\" class=\"markedContent\"><br role=\"presentation\" \/><span dir=\"ltr\" role=\"presentation\">Phone +49 89 58 8088 471<\/span><\/span><span id=\"page36R_mcid10\" class=\"markedContent\"><br role=\"presentation\" \/><span dir=\"ltr\" role=\"presentation\">E<\/span><span dir=\"ltr\" role=\"presentation\">&#8211;<\/span><span dir=\"ltr\" role=\"presentation\">mail:<\/span><\/span><span id=\"page36R_mcid11\" class=\"markedContent\"> <span dir=\"ltr\" role=\"presentation\"><a href=\"mailto:info@adivo.vet\">info@adivo.vet<\/a><\/span><\/span><\/p>\n<p>&nbsp;<\/p>\n<p><em><a href=\"https:\/\/www.fyonibio.com\/2023\/01\/09\/adivo-agreement\/\" target=\"_blank\" rel=\"noopener noreferrer\"><span style=\"font-size: 12px;\"><span style=\"font-size: 14px;\">Source: FyoniBio<\/span><\/span><\/a><\/em><\/p>\n<div class=\"annotationLayer\" data-main-rotation=\"0\"><\/div>\n","protected":false},"excerpt":{"rendered":"<p>FyoniBio GmbH, member of the Bio-PAT network, signed a Service Agreement with adivo.It covers the generation of a production cell line for their canine therapeutic mAb candidate. For the project, [&hellip;]<\/p>\n","protected":false},"author":3,"featured_media":7155,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_exactmetrics_skip_tracking":false,"_EventAllDay":false,"_EventTimezone":"","_EventStartDate":"","_EventEndDate":"","_EventStartDateUTC":"","_EventEndDateUTC":"","_EventShowMap":false,"_EventShowMapLink":false,"_EventURL":"","_EventCost":"","_EventCostDescription":"","_EventCurrencySymbol":"","_EventCurrencyCode":"","_EventCurrencyPosition":"","_EventDateTimeSeparator":"","_EventTimeRangeSeparator":"","_EventOrganizerID":[],"_EventVenueID":[],"_OrganizerEmail":"","_OrganizerPhone":"","_OrganizerWebsite":"","_VenueAddress":"","_VenueCity":"","_VenueCountry":"","_VenueProvince":"","_VenueState":"","_VenueZip":"","_VenuePhone":"","_VenueURL":"","_VenueStateProvince":"","_VenueLat":"","_VenueLng":"","_VenueShowMap":false,"_VenueShowMapLink":false,"footnotes":""},"categories":[1],"tags":[],"class_list":["post-7149","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-allgemein"],"featured_image_src":{"landsacpe":["https:\/\/bio-pat.org\/wp-content\/uploads\/2023\/01\/FyoniBio-Kooperation_adivo.jpg",298,199,false],"list":["https:\/\/bio-pat.org\/wp-content\/uploads\/2023\/01\/FyoniBio-Kooperation_adivo.jpg",298,199,false],"medium":["https:\/\/bio-pat.org\/wp-content\/uploads\/2023\/01\/FyoniBio-Kooperation_adivo.jpg",298,199,false],"full":["https:\/\/bio-pat.org\/wp-content\/uploads\/2023\/01\/FyoniBio-Kooperation_adivo.jpg",298,199,false]},"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.8 - 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