8th BioProScale Symposium 2024 – Scaling Down and Up of Bioprocesses: Strategies, Tools and Process Performance

The 8th BioProScale Symposium 2024 is an event on industrial scale bioprocessing with a long scientific tradition. Target groups are experts from research & development and industrial practice in bioprocessing of pharmaceuticals, food, feed and renewables.
Join the 8th BioProScale Symposium and enjoy the lectures and poster sessions, get insights into the newest technologies at the accompanying exhibition and network with the other participants.
Press Release

Topics 2024

Area 1: Scale up and industrial scale processes
Process performance across scales and process modes, bioreactor/bioprocess modelling, description of cell and reactor heterogeneities at large scale, sustainability of bioprocesses
Area 2: Bioprocess scale down
Scale down approaches, small scale simulators of industrial scale processes, scale related cell physiology, validation of scalability, high throughput bioprocessing concepts 
Area 3: Process-driven cell performance
Analysis and modelling of cell populations, optimization and design of cell-cell and cell-bioreactor interactions, microbial co-cultivation
Area 4: Integrated bioprocesses
Circular economy concepts, bioprocess coupling, continuous operation, integrating upstream and downstream operations across scales
Area 5: Process analytical technologies (PAT)
Sensor integration, data modelling fusion, PAT for faster scale down and up of bioprocesses

Program
Poster List
Practical Information
Information for Exhibitor & Sponsors
Registration

Meet our Bio-PAT members

The following members exhibit:
– ANiMOX GmbH at booth A1
– BlueSens gas sensor GmbH at booth B3
– Knick Elektronische Messgeräte GmbH & Co. KG at booth B1
– Celltainer Biosolutions GmbH will be represented by BIONET at booth B11

Expect the following talks of our members:
– 09.04.2024 at 16:25: Morphology control for supporting scalability of Aspergillus niger cultures (Tolue Kheirkhah, Chair of Bioprocess Engineering, Technische Universität Berlin)
– 10:04.2024 at 10:15: Small scale models for process intensification: How to migrate a months-long perfusion process to intensified fed-batch (Lena Tholen – FyoniBio GmbH)
– 10.04.2024 at 15:10: Workflow automation for reproducible high-throughput cultivations (Lucas Kaspersetz, Chair of Bioprocess Engineering, Technische Universität Berlin)
– 11.04.2024 at 11:10: Production of PUFAs from dark fermentation effluent with Schizochytrium limacinum SR21 (Simon Täuber, Chair of Bioprocess Engineering, Technische Universität Berlin)
– 11.04.2024 at 11:35: Bioprocess optimization for lactic and succinic acid production from a pulp and paper industry side stream (Agata Olszewska-Widdrat, Leibniz Institute for Agricultural Engineering and Bioeconomy)

And have a look on the following posters of the Bio-PAT members:
– Biophotonics Diagnostics GmbH: P31: Real-time analysis of multicomponent bioprocesses using Raman spectroscopy and RAMANMETRIX^(TM)
– Chair of Bioprocess Engineering, Technische Universität Berlin with the KIWI-biolab:
P06: Challenges of bioprocess scale-down on an automated Platform – Linda Lantian Cai
P22: Membrane-free dissolved hydrogen monitoring in hydrolytic and methanogenic bioprocesses – Eike Janesch
P23: Investigating signal attenuation in raman spectra of bacterial fermentations – Christoph Lange
P26: Robust tube-based MPC for controlling bioprocesses under uncertainty – Niels Krausch
P30: Enzyme-Mediated Exponential Glucose Release: A Model-Based Strategy for Continuous Defined Fed-Batch in Small-Scale Cultivations – Annina Kemmer
P33: Data Management in Automated transdisciplinary laboratories – Simon Seidel
P34: Silicon-Based Photonic Biosensors for Label-Free Detection of Microorganisms – Philipp Schrenk
P39: Development of a non-canonical amino acid-labeled [NiFe]-hydrogenase production system in Escherichia coli – Qin Fan
P40: Heterologous production of an active hydrogenase using lactose-based autoinduction – De La Fuente Kratzborn Francisco
P41: Bioprocess development to produce a hyperthermostable S-methyl-5′-thioadenosine phosphorylase in Escherichia coli – Julia Schollmeyer
P48: Purine nucleoside antibiotics: recent synthetic advances harnessing chemistry and biology – Jonas Motter
P49: Biocatalytic nucleobase diversification of 4’-thianucleosides and de novo RNA synthesis detection with 5-ethynyl-4’-thiouridine in proliferating HeLa cells – Sarah von Westarp
P52: Substituting raw materials: Animal by-product streams for polyhydroxyalkanoate production – Saskia Waldburger

Confirmed Plenary Talks

• Managing cell population entropy: navigating from ecosystems to bioprocesses
  Frank Delvigne (University of Liège, Gembloux Agro-Bio Tech, Département GxABT, Microbial technologies)
• Proper scale down: a prerequisite for engineering robust microbial chassis and for model-based prediction of industrial scale performance
  Ralf Takors (University of Stuttgart, Institute of Biochemical Engineering)
• Single-use bioreactors: Applications and scaling-up
  Regine Eibl-Schindler (ZHAW School of Life Sciences and Facility Management, Section for Cell Cultivation Technique):
• How fundamental research on multiphase flows can support a reliable scale-up
  Michael Schlüter (Hamburg University of Technology, Institute of Multiphase Flows)
• Towards closed-loop bioprocess development: Robotic workflows for automated Design-Build-Test-Learn cycles
  Marco Oldiges (Forschungszentrum Jülich GmbH, Head of Bioprocesses and Bioanalytics)
• The role of bioeconomy on the path to net-zero
  Daniela Thrän (Helmholtz-Zentrum für Umweltforschung, UFZ)

Exhibition and sponsoring options

Don’t miss the opportunity to present your company, your products and services to your target group in the accompanying exhibition in the conference venue or as a conference sponsor.
Sponsorship opportunities include advertisements in the abstract booklet (PDF) and/or on the conference website and a booth in the exhibition.

Check also the BioProScale LinkedIn group for regular updates!

The 8th BioProScale Symposium is jointly organized by the Technische Universität Berlin, Chair of Bioprocess Engineering, the Institute for Biotechnology and Fermentation in Berlin (IfGB), the BioProScale e.V. and Bio-PAT. e.V.

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