Chair of Bioprocess Engineering, Technische Universität Berlin, Institute of Biotechnology – Short Profile

Profile Logo Bioprocess Engineering, Institute of Biotechnology, TU Berlin

Website: https://www.bioprocess.tu-berlin.de/menue/home/

Location of the Chair: Berlin

Year of Foundation: Realignment since 2008

Number of employees at the Chair: 67 (incl. Bachelor and Master students)

Main contact person in the Bio-PAT network: Prof. Peter Neubauer

Position: Head of the Chair of Bioprocess Engineering and Professor at the Chair of Bioprocess Engineering

 

Products / Product Groups / Services / Competencies:

– Competencies:

  • Cultivation of and process development with various microorganisms (bacteria, yeasts, fungi, lichens, plant cells)
  • Development and application of process analytical technologies (multiposition and optical sensors for in-situ real-time monitoring and analysis of gradients as well as analysis of physiological and morphological cell changes for process monitoring and optimization)
  • Bioprocess scale-up/-down (investigation of oscillating conditions & gradients and their effects on cells as well as population heterogeneities)
  • Development of and cultivation in single-use bioreactors
  • Automated bioprocess development with mathematical models and artificial intelligence (liquid handling, platforms, parallelization of cultivations, screenings, process analyses)
  • Bioprocess modeling (data correlations, model reduction, modeling of scale-up/-down using kinetic models)
  • Applied biocatalysis (recombinant production of biocatalysts, protein expression, metabolic engineering, synthesis of chemical molecules)

Chair of Bioprocess Engineering, TU Berlin

– Equipment:

  • Bioreactors of various sizes and configurations (10 mL – 150 L)
  • Systems for bioprocess analytics: multiparameter sensors, sensors for physico-chemical process parameters, single-cell analytics (e.g., flow cytometry, in-situ probes, microscopic techniques), electro-optical methods, HPLC, GC-MS/FID, CEDEX-Pro media analyzer
  • Scale-down bioreactor & single-use bioreactors
  • Automated robotic laboratory for bioprocess development and corresponding software for modeling

Looking for:

– cooperation partners in the mentioned fields of competence for:

  • Joint research projects
  • Proof-of-concept trials for technologies or developments of external partners
  • Joint application notes