1st Berlin-BioTECH Symposium “Difficult to Express Proteins”
The 1st Berlin-BioTECH Symposium “Difficult to Express Proteins” took place on December 10-11, 2024 in Berlin. The symposium focused on interesting and difficult to express protein expression systems and strategies. Beside the great talks, a lot of room for discussion was given on both days for the 80 participants from 8 countries. A lab tour through the facilities of the Chair of Bioprocess Engineering rounded the event off. Bio-PAT and the member Enpresso GmbH were present as exhibitors.
Background for the 1st Berlin-BioTECH Symposium:
Recombinant proteins are the most important biotechnological products. They are particularly important for medical and biotechnological applications. As almost any chemical reaction can be catalyzed by proteins under mild conditions, they represent an environmentally friendly alternative to chemical synthesis. In order to meet the demand for the required proteins, appropriate bioprocesses must be developed for their efficient and cost-effective production on an industrial scale. On the one hand, Escherichia coli is a promising host for heterologous protein production as it can be grown very fast to very high cell densities, on the other hand heterologous production of many interesting proteins is challenging and they are considered as “difficult-to-express-proteins”. The symposium addressed such challenges, e.g. formation of disulfide bonds, non-canonical amino acids, glycosylation, production of membrane proteins, metalloproteins or super large proteins.
The event was mainly organized by BioProScale e.V., the Chair of Bioprocess Engineering, TU Berlin, and Bio-PAT e.V.
More information and program (PDF)
Handout (PDF)
Foto Galery
(©Prof. Peter Neubauer, Dr. Anika Bockisch, click on the photos to enlarge.)
